Gene-Editing Nanoplatform Transforms Cancer Cells Into Vaccine Targets in Metastasis Breakthrough
Researchers have created a breakthrough gene-editing platform that reprograms cancer cells’ genetic tolerance to treatment. The technology transforms tumors into immunotherapy-responsive targets while creating durable immune memory against recurrence.
Gene-Editing Platform Overcomes Cancer Treatment Resistance
Scientists have developed a novel nanoplatform that uses CRISPR gene editing to transform how cancers respond to immunotherapy, according to reports published in Nature Biomedical Engineering. The technology targets haem oxygenase-1 (HO-1), a key enzyme that tumors use to develop resistance to reactive oxygen species, which are crucial components of many cancer treatments.