Scientists Bridge Neural Activity and Molecular Structure with Groundbreaking Imaging Technique
A revolutionary correlative imaging approach has enabled scientists to directly link neuronal electrical activity with molecular structure. The new technique reveals distinct ribosomal landscapes in neurons with different electrophysiological properties, opening new avenues for neuroscience research.
Breakthrough Method Connects Neuronal Function and Structure
Scientists have developed a groundbreaking correlative imaging technique that directly bridges the gap between neuronal electrical activity and molecular structure, according to research published in Nature Communications. The new method, termed Correlative Voltage imaging and cryo-ET (CoVET), combines voltage imaging with cryo-electron tomography to simultaneously capture electrical activity and high-resolution molecular details within the same neurons.