Researchers from Nobel Laureate David Baker’s lab have successfully used AI to design antibodies that bind to their targets. The breakthrough could transform how we develop treatments for everything from flu to bacterial toxins. The software is freely available on GitHub for anyone to use.
Researchers have created a breakthrough gene-editing platform that reprograms cancer cells’ genetic tolerance to treatment. The technology transforms tumors into immunotherapy-responsive targets while creating durable immune memory against recurrence.
Scientists have developed a novel nanoplatform that uses CRISPR gene editing to transform how cancers respond to immunotherapy, according to reports published in Nature Biomedical Engineering. The technology targets haem oxygenase-1 (HO-1), a key enzyme that tumors use to develop resistance to reactive oxygen species, which are crucial components of many cancer treatments.
Revolutionizing Proteomic Data Processing In a significant breakthrough for biotechnology and analytical science, researchers have developed AlphaDIA, an innovative framework…
Researchers have demonstrated a new epigenetic editing approach that provides durable gene silencing in primary human T cells without causing DNA damage. The technology, called CRISPRoff, maintains gene repression through multiple cell divisions and shows minimal cellular toxicity compared to traditional CRISPR-Cas9 methods. This breakthrough could significantly advance cell therapy development and genetic research applications.
Scientists have developed a groundbreaking epigenetic editing technology that can permanently silence genes in human immune cells without altering the underlying DNA sequence, according to research published in Nature Biotechnology. The approach, reportedly called CRISPRoff, enables durable gene repression that persists through approximately 30-80 cell divisions, representing a significant advancement over previous temporary gene silencing methods.
The New Frontier of Bio-Manufacturing In a groundbreaking shift from traditional chemical processes, synthetic biology companies are demonstrating that living…
